Saving lives through groundbreaking research
The Institute of Cancer Research (ICR), our current funding priority, demonstrates the results that are possible when brilliant scientific minds come together to focus on cancer research.
With its unparalleled record in developing lifesaving cancer therapeutics and identifying cancer causing genes, the ICR has never been closer to achieving its vision that people may live their lives free from the fear of cancer as a life threatening disease.
Learn about the ICR’s significant breakthroughs:
New drug combats previously untreatable prostate cancers
In a phase I trial, abiraterone benefited up to 70% of men with aggressive, and potentially fatal, prostate cancer.
Childhood leukemia stem cells develop in pregnancy
This study of twins in which one has leukemia has identified the critical stem cells that initiate the disease and maintain it in a covert state for several years.
Lox enzyme crucial for cancer spread
"This new discovery provides real hope that we can develop a drug which will fight the spread of cancer." Dr. Janine Erler, Hypoxia and Metastasis Team Leader
Computation joins the fight against cancer
ICR scientists can use computer algorithms to map the ‘signaling networks’ of cells; this knowledge could lead to enhanced drug development and cancer treatments.
Olaparib, a promising new drug targeting cancer weakness
ICR scientists have a developed olaparib, a new drug that has shown promising clinical trials results in treating BRCA1/2-related breast, ovarian and prostate cancers.
Current research and achievements
- Colorectal, leukemia and lung cancer genes found
- Seven new prostate cancer genetic variants found
- Childhood leukemia stem cells develop in pregnancy
- Timing of key genetic events in leukemia evolution revealed
More research stories:
Some of ICR's key achievements
1930s: The identification of the potential link between smoking and lung cancer
1950s: The development of three successful drugs still used in cancer treatment
1960s: The discovery that the basic cause of cancer is damage to DNA
1970s: The development of carboplatin, a drug used to treat a wide range of solid tumors
1995-present: The isolation of many cancer genes, including BRCA2
Last 5 years: The discovery of two drug development candidates per year (on average)
